Ma bedeli kartaa saacadaada Epigenetic?

Gabowgu waa qayb dabiici ah oo nolosha ka mid ah lamana joojin karo. Ama ugu yaraan, taasi waa waxa aan ku fikiri jirnay. Cilmi-baarayaasha Intervene Immune, Stanford, Jaamacadda British Columbia, iyo UCLA waxay aaminsan yihiin in saacada epigenetic-ka la bedeli karo, taas oo soo jeedinaysa in weli ay jiraan siyaabo ay dadku ku noolaan karaan waqti dheer. Maqaalka soo socda, waxaan ka wada hadli doonaa natiijooyinka la xidhiidha epigenetics iyo gabowga.

 

Waa maxay saacadda Epigenetic?

 

Saacadda epigenetic waa cabbiraadda da'da noolaha oo loo isticmaali karo in lagu qiyaaso da'da taariikheed ee bini'aadamka ama noolaha kale iyadoo la tijaabinayo qaabab badan oo methyl DNA ah. Inkasta oo da'da lagu qiyaaso saacadda epigenetic ay si joogto ah ula xiriirto da'da taariikheed, si buuxda looma fahmin haddii astaamaha methylation DNA ee saacadda epigenetic ay si toos ah ula xiriiraan gabowga.

 

Sannado badan, cilmi-baarayaashu waxay arkeen isbeddellada la xiriira da'da ee muujinta hiddaha iyo methylation DNA. Si kastaba ha ahaatee, fikradda ah in la isticmaalo "saac epigenetic" si ay u awoodaan in ay qiyaasaan da'da taariikhiga ah iyada oo la tijaabinayo dhowr nooc oo DNA methylation ah ayaa markii ugu horeysay soo jeediyay Steve Horvath halkaas oo ay ka heshay caan ka dib markii cilmi-baaristiisa 2013 lagu daabacay joornaalka Genome Biology.

 

Saacadaha Epigenetic waxaa loo adeegsadaa cilmi baarista dambiyada si loo go'aamiyo da'da qof aan la garanayn iyada oo loo marayo dhiig ama muunado kale oo bayooloji ah oo ku yaal goobta dembiga iyo shaashadaha ogaanshaha si loo go'aamiyo khatarta sii kordheysa ee cudurrada la xidhiidha gabowga, oo ay ku jiraan noocyo kala duwan oo kansar ah. Saacadaha Epigenetic waxay sidoo kale muujin karaan in dhowr dabeecadood ama daaweyn ay saameyn karaan da'da epigenetic.

 

Da'da Epigenetic ma waxay la xiriirtaa da'da taariikheed?

 

Sababta ugu weyn ee saacadaha epigenetic iyo methylation DNA loo isticmaalo si loo qiyaaso da'da taariikheed ee bini'aadamka ama noolaha kale waa inay si fiican ula xiriiraan da'da taariikhiga ah ee maadooyinka la tijaabiyey. Daraasaddii ugu horreysay ee cilmi-baarista ee saacadda epigenetic ee Steve Horvath lagu daabacay 2013 waxaa ku jiray 353 goobood oo CpG ah oo laga aqoonsaday daraasadihii hore ee cilmi-baarista.

 

Goobahan, 193 waxay noqonayaan methylated badan oo da' ah iyo 160 waxay noqdaan methylated yar, taas oo horseedaysa qiyaasta da'da methylation DNA ee loo isticmaalo si loo go'aamiyo saacadda epigenetic. Dhammaan cabbirada natiijada, oo ay ku jiraan dhammaan da'da maaddooyinka, Horvath wuxuu arkay 0.96 isku-xirnaanta da'da epigenetic ee uu xisaabiyay iyo da'da taariikhiga ah ee runta ah, oo leh heerka qaladka 3.6 sano.

 

Saacadaha epigenetic ee hadda jira ayaa sidoo kale la qiimeeyaa si ay uga caawiyaan sii wanaajinta saadaasha da'da iyo sidoo kale ogaanshaha iyo/ama awoodaha saadaalinta ee imtixaanadan. Qiimaynta dheeraadka ah ee la isticmaalayo hababka NGS ayaa ugu dambeyntii awood u leh inay hagaajiyaan saacadaha epigenetic, iyaga oo ka dhigaya kuwo aad u faahfaahsan iyada oo la kordhinayo qiimeynta goobaha DNA-da ee methylation dhammaan goobaha CpG ee genome.

 

Ma bedeli karnaa Saacadaheena Epigenetic?

 

Daraasadaha cilmi-baarista ayaa muujiyay in kansarku uu bedeli karo saacadda epigenetic. Aragtiyadani waxay soo jeedinayaan in saacadda epigenetic ay isbeddeli karto xaaladaha qaarkood. Sidaa darteed, waxaa suurtogal ah in saacadda epigenetic lagu maareeyo iyada oo loo marayo isbeddelka habdhaqanka ama xeeladaha daaweynta si loo yareeyo ama laga yaabo inay dib u dhigto, taas oo u oggolaanaysa bini'aadamka inay ku noolaadaan nolol dheer oo caafimaad leh.

 

 

Cilmi-baarayaashu waxay aaminsan yihiin in saacada epigenetic-ka la bedeli karo. Maqaalka soo socda, waxaan ka wada hadalnay natiijooyinka la xidhiidha epigenetics iyo gabowga. Saacadda epigenetic waa cabbiraadda da'da noolaha oo loo isticmaali karo in lagu qiyaaso da'da taariikheed ee bini'aadamka ama noolaha kale iyadoo la tijaabinayo qaabab badan oo methyl DNA ah. Sababta ugu weyn ee saacadaha epigenetic iyo methylation DNA loo isticmaalo si loo qiyaaso da'da taariikheed ee bini'aadamka ama noolaha kale waa inay si fiican ula xiriiraan da'da taariikhiga ah ee maadooyinka la tijaabiyey. Saacadaha epigenetic ee hadda jira ayaa sidoo kale la qiimeeyaa si ay uga caawiyaan sii wanaajinta saadaasha da'da iyo sidoo kale ogaanshaha iyo/ama awoodaha saadaalinta ee imtixaanadan. Daraasadaha cilmi-baarista ayaa muujiyay in kansarku uu bedeli karo saacadda epigenetic. Sidaa darteed, waxaa suurtogal ah in saacadda epigenetic lagu maareeyo iyada oo loo marayo isbeddelka habdhaqanka ama xeeladaha daaweynta si loo yareeyo ama laga yaabo inay dib u dhigto, taas oo u oggolaanaysa bini'aadamka inay ku noolaadaan nolol dheer oo caafimaad leh. Beddelidda saacadaha epigenetic-ka, xirfadlayaasha daryeelka caafimaadku waxay sidoo kale awood u yeelan karaan inay nidaamiyaan arrimaha caafimaadka da'da, sida caabuqa iyo xanuunka wadajirka. Kuwani waxay noqon karaan kuwo waxtar u leh daryeelka xanuunka loo yaqaan 'chiropractic care', doorasho daaweyn kale oo adeegsata hagaajinta laf dhabarta si ay si taxadar leh u soo celiso isku-dheelitirka laf-dhabarka.- Dr. Alex Jimenez DC, CCST Insight

 

 

 

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� 1 canab, diiray oo la jarjaray
� 1 tufaax, la dhaqay oo la jarjaray
� 1 dabocase oo dhan, iyo caleemo haddii aad haysatid, dhaq oo jarjar
1-inch buro oo sinjibiil ah, la luqluqsaday, diiray oo la jarjaray

Casiir dhammaan maaddooyinka ku jira casiirka tayada sare leh. Sida ugu fiican isla markiiba loo adeego.

 

 

Hal karooto oo keliya ayaa ku siinaysa dhammaan fitamiin A aad maalin kasta qaadato

 

Haa, cunida hal mar oo karsan oo ah 80g (2oz) karooto ayaa ku siinaysa beta-carotene ee jidhkaaga si uu u soo saaro 1,480 micrograms (mcg) oo fitamiin A ah (oo lagama maarmaan u ah cusboonaysiinta unugyada maqaarka). Taasi waa in ka badan inta lagu taliyay qaadashada maalinlaha ah ee fitamiin A ee Maraykanka, kaas oo qiyaastii ah 900mcg. Way fiican tahay in la cuno karootada la kariyey, maadaama tani ay jilciso gidaarada unugyada taasoo u oggolaanaysa in beta-carotene badan la nuugo. Ku darida cuntooyinka ka caafimaad badan cuntadaada waa hab fiican oo lagu wanaajiyo caafimaadkaaga guud.

 

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Baaxadda macluumaadkayagu waxay ku xaddidan tahay xanuunka loo yaqaan 'chiropractic, musculoskeletal', dawooyinka jireed, fayoobaanta, iyo arrimaha caafimaadka xasaasiga ah iyo/ama maqaallada daawada shaqeynta, mowduucyada, iyo doodaha. Waxaan isticmaalnaa borotokoolka caafimaadka iyo fayo-dhowrka si loo daweeyo oo loo taageero daryeelka dhaawacyada ama cilladaha habka muruqyada. Qoraaladayada, mawduucyada, mawduucyada, iyo fikradaha waxay daboolayaan arrimaha caafimaadka, arrimaha, iyo mawduucyada la xidhiidha oo taageera si toos ah ama si aan toos ahaynba baaxadda hawl-qabadkeena caafimaad. daraasado taageeraya qoraaladayada. Waxaan sidoo kale ka dhignaa nuqullo ka mid ah daraasadaha cilmi-baarista ee taageeraya oo ay heli karaan guddiga iyo dadweynaha haddii la codsado. Waxaan fahamsanahay inaan daboolno arrimaha u baahan sharraxaad dheeri ah oo ku saabsan sida ay u caawin karto qorshe daryeel gaar ah ama borotokoolka daaweynta; sidaas darteed, si aad uga wada hadasho mawduuca kor ku xusan, fadlan xor u noqo inaad weydiiso Dr. Alex Jimenez ama nala soo xiriir 915-850-0900. Bixiyeyaasha (-yaasha) Shatiga ku haysta Texas*& New Mexico*�

 

Waxaa soo diyaariyay Dr. Alex Jimenez DC, CCST

 

Tixraacyo:

 

• Shaqaalaha Motif ee Firfircoon. �Runtii ma beddeli kartaa da'daada Epigenetic?� Motif firfircoon, 1 Oct. 2019, www.activemotif.com/blog-reversing-epigenetic-age#:~:text=Epigenetic%20clocks%20are%20a%20measure,certain%20patterns%20of%20DNA%20methylation.
• Pal, Sangita, iyo Jessica K Tyler. �Epigenetics iyo gabowga.� Horumarka Sayniska, Ururka Maraykanka ee Horumarinta Sayniska, 29 Luulyo 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4966880/.
• Matloff, Ellen. �Muraayad, Muraayad, gidaarka: Epigenetics of Aging.� Forbes, Forbes Magazine, 25 Jan. 2020, www.forbes.com/sites/ellenmatloff/2020/01/24/mirror-mirror-on-the-wall-the-epigenetics-of-aging/#75af95734033.
• Dowden, Angela. �Bunku waa khudrad iyo xaqiiqooyin kale oo aan la rumaysan karin oo run ah Qaab nololeedka MSN, 4 Juun 2020, www.msn.com/en-us/foodanddrink/did-you-know/coffee-is-a-fruit-and-other-unbelievably-true-food-facts/ss-BB152Q5q?li=BBnb7Kz&ocid =mailsignout#image=24.