Bifidobacteria iyo habka mindhicirka

Ma dareemaysaa:

• Calool xanuun, gubasho, ama xanuun 1-4 saacadood ka dib cuntada?
• Dhibaatooyinka dheefshiidka ayaa hoos u dhaca nasashada ama nasashada?
• Calool-xumada iyo buuxnaanta waxay qaadataa 2-4 saacadood cuntada kadib?
• Xidid xad-dhaaf ah, daacasho, ama barar?
• Calool-baxa ka dib qaar ka mid ah probiotics ama supplements dabiiciga ah?

Haddii aad la kulanto mid ka mid ah xaaladahan, markaas waxaa laga yaabaa inay sabab u tahay hoos u dhaca nidaamka mindhicirka ee Bifidobacteria.

Microbiome-ka jidhku waxa uu hoy u yahay noocyo badan oo bakteeriyayaal ah kuwaas oo gacan ka geysta gacan ka geysta sifooyinkooda gaarka ah ee kor u qaada caafimaadka. Noocyada bakteeriyadani waxay caawiyaan jidhka iyagoo hubinaya in xubin kasta iyo nidaamka jidhku u shaqeeyo sida saacadda oo kale. Marka uu jirku ka kooban yahay bakteeriyada pathogenic ee waxyeelada leh, waxay keeni kartaa in jirku uu shaqeyn waayo, cudurro daba-dheeraada ayaa billaabaya inay sameysmaan oo xitaa waxyeello u geystaan ​​jirka.

Daraasado cilmi baaris ayaa la helay marka la eego in tirada noocyada bakteeriyada ee ku jira microbiota mindhicirka bini'aadamka ay u badan tahay inay ka badan karaan 10⁴. Taas macnaheedu waa in ugu yaraan toban jeer ay ku jiraan unugyada bakteeriyada ee xiidmaha bini'aadamka marka loo eego tirada unugyada bini'aadamka. Waxaa jira xitaa in ka badan 100 jeer qiyaasta microbiome-ka genomic sida genome-ka aadanaha. La yaab in kastoo, ay jiraan xitaa daraasado badan kuwaas oo ogaaday in ay jirto saamiga siman ee bini'aadamka iyo unugyada bakteeriyada.

bifidobacteria

Iyadoo aan loo eegin tirada, microbiome-ga mindhicirka ayaa weli leh noolaha ugu badan ee jirka. Marka mindhicirka iyo jidhku si fiican isku dheelitiraan, waxaa jira noocyo kala duwan oo microbes ah oo siin kara jidhka la xoojiyay oo la xoojiyay kaas oo taageeri kara habka difaaca jirka, la dagaallama caabuqa jirka soo galay. Microbes-ku waxay siin karaan mindhicirka xayndaab ka hortagga cudurada faafa, waxayna caawiyaan dheef-shiid kiimikaadka iyo sidoo kale soo saarista nafaqooyinka muhiimka ah ee jidhku u shaqeeyo. Iyada oo tirada badan ee noocyada bakteeriyada ee mindhicirka iyo jidhka labadaba, waxaa jira mid ka mid ah noocyada bakteeriyada ee jirka oo aad muhiim ugu ah jirka caafimaadka qaba. Waxaa loo yaqaan Bifidobacteria, noocyada bakteeriyadani waxay door weyn ku leeyihiin microbiome-ka jirka.

Bifidobacteria waa nooc asal ah oo asal ah oo aad u badan oo ka mid ah noocyada bakteeriyadan ee ku jira mindhicirka, tiradooda iyo sidoo kale noocyadooda, ayaa la bedeli karaa da'da. Bifidobacteria waxay si cad ugu badan tahay mindhicirka. Waxaase la yaab leh, nooca Bifidobacteria waxaa laga heli karaa dhallaanka naaska la nuujinayo waxayna ku jiraan mindhicirrada. Maadaama oligosaccharides fucosylated ee caanaha naaska ku jira ay caawiyaan dhallaanka korriinka, waxay hoos u dhigi doontaa B. longum. Iyada oo gumeysiga Bifidobacteria ee dhallaanka ay noqdeen kuwo si fiican loo gumaysto ilaa noocyada B. catenulatum iyo B. qaan-gaarnimada ay jiraan sanadaha qaangaarka, waxayna u muuqataa in B. longum ay weli tahay mid aad u badan inta lagu jiro nolosha aadanaha.

Faa'iidooyinka Bifidobacteria ee Dhallaanka

Marka haweeneydu uur yeelato, Bifidobacteria waxay noqotaa cirifka ugu horreeya ee bakteeriyada la wareejiyo. Bakteeriyadani waxay hubisaa in laga soo wareejinayo kanaalka xubinta taranka hooyada, caanaha naaska, mandheerta, iyo dheecaanka amniotic loona wareejiyo ilmaha ku koraya hooyada. Marka tani ay socoto habka, waxay muujineysaa muhiimada dhalashada siilka iyo naas nuujinta si loo dhiso microbiome caafimaad leh, koraya. Cilmi baaris ayaa muujinaya in aasaaska Bifidobacteria ee dhallaanka ay dib u dhigi karto haddii hooyada ilmaha koraya ay leedahay polymorphism-ka FUT2 (Fucosyltransferase 2). Waxa uu hidde-sidahani sameeyo waa in uu dejiyo ensaymes si loogu wareejiyo fucose glycans ee caanaha naaska, ka dibna glycan-ka ayaa markaa metabolized by Bifidobacteria si uu jidhku u koro oo caafimaad u yeesho.

Daraasado ayaa helay in qaar ka mid ah noocyada Bifidobacteria sida B. breve, ay leeyihiin antimicrobial iyo immunomodulatory Properties kuwaas oo muhiim u ah marxaladaha nolosha ee jidhka bini'aadamka halkaas oo difaacu uu daciifo ama xitaa waxyeello u geysan karo. Dhallaanka, noocyada Bifidobacteria ayaa xitaa aad u qiimo badan, maadaama ay ka caawiyaan horumarinta habka difaaca cusub mana awoodaan inay gudbiyaan iska caabbinta antibiyootiga. Tani waxay khusayn kartaa qaar ka mid ah noocyada probiotic ee jirka. Si kastaba ha ahaatee, nooca bakteeriyada B. breve, si kastaba ha ahaatee, daraasado ayaa lagu ogaaday in noocyada bakteeriyadani ay muhiim u yihiin ka hortagga xaalado badan oo caloosha ah oo carruurta ah.

Faa'iidooyinka Bifidobacteria ee Dadka Waaweyn

Marka ay timaado Bifidobacteria ee dadka qaangaarka ah, tirada bakteeriyada ayaa hoos u dhacda sababtoo ah gabowga dabiiciga ah. Si kastaba ha ahaatee, Bifidobacteria waxay weli bixisaa qadar siman oo faa'iido leh oo leh waxqabadyo badan oo bayooloji ah kuwaas oo ka hortagi kara qaar ka mid ah xaaladaha caloosha ee ugu caansan. Daraasado ayaa muujiyey in Bifidobacteria ay muujin karto natiijooyin rajo leh oo ka hortagga kansarka mindhicirka waxaana loo isticmaali karaa daaweyn isku dhafan. Daraasaduhu waxay xitaa muujinayaan sida Bifidobacteria ay u muujin karto waxqabadka anti-mutagenic, ka ilaalinta DNA-da waxyeellada kansarka, iyo xitaa waxay joojisay saameynta genotoxic-ka ee kansarka.

Daraasad kale ayaa xitaa muujisay in Bifidobacteria ay ka hortagi karto oo ay yarayn karto shubanka uu keeno Clostridium difficile. Natiijooyinku waxay muujinayaan in daawaynta Bifidobacteria ay si weyn u dhimi karto tirada Clostridium difficile iyo inay hoos u dhigto titres-ka sunta ah ee clostridia.

Ugu Dambeyn

Bifidobacteria waa bakteeriya aad u weyn oo mas'uul ka ah ilaalinta nidaamka jirka iyo mindhicirka caafimaadka qaba. Marka jirku uu la tacaalayo caabuqa ama uu leeyahay arrimaha caloosha, markaa cirridka bifidobacteria ayaa sidoo kale saameyn doona. Bakteeriyadani waxay ku jirtaa jidhka bini'aadamka laga bilaabo yaraanta ilaa qaangaarnimada, waxayna si dabiici ah hoos ugu dhacdaa gabowga. Qaar wax soo saarka waxay ku takhasuseen inay caawiyaan habka caloosha iyo mindhicirka iyagoo siinaya nafaqooyinka hypoallergenic, cofactors enzymatic, horudhacyada dheef-shiid kiimikaadka, iyo nafaqeeyayaalka jidhku u baahan yahay.

Baaxadda macluumaadkayagu waxay ku xaddidan tahay xanuunka loo yaqaan 'chiropractic, musculoskeletal', iyo arrimaha caafimaadka neerfaha ama maqaallada daawada shaqeynta, mowduucyada, iyo doodaha. Waxaan isticmaalnaa borotokool caafimaad oo shaqeynaya si aan u daaweyno dhaawacyada ama cilladaha habka muruqyada. Xafiiskayagu waxa uu sameeyay isku day macquul ah oo uu ku bixinayo tixraacyo taageero ah waxana uu aqoonsaday daraasadda cilmi-baadhiseed ee la xidhiidha ama daraasadaha taageeraya qoraaladayada. Waxaan sidoo kale ka dhignaa nuqullo ka mid ah daraasadaha cilmi-baarista ee taageeraya oo ay heli karaan guddiga iyo dadweynaha haddii la codsado. Si aad uga hadasho mawduuca kor ku xusan, fadlan xor u noqo inaad weydiiso Dr. Alex Jimenez ama nala soo xiriir 915-850-0900.

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Tixraacyo:

Arboleya, Silvia, iyo al. �Dadka Bifidobacteria ee Caafimaadka Dadka iyo Gabowga.� Xannibaadyada ku jira Microbiology, Frontiers Media SA, 19 Aug. 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4990546/.

Bozzi Cionci, Nicole, iyo al. �Daweynta Microbiology: Doorka Bifidobacterium Breve Sida Kaabitaanka Cunnada ee Ka-hortagga/Daawaynta Cudurrada Carruurta.� Nafaqooyinka, MDPI, 10 Noofambar 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC6265827/.

O'Callaghan, Amy, iyo Douwe van Sinderen. �Bifidobacteria iyo Doorkooda Xubna ka ah Microbiota Gut ee Bani'aadamka. Xannibaadyada ku jira Microbiology, Frontiers Media SA, 15 Juun 2016, www.ncbi.nlm.nih.gov/pmc/articles/PMC4908950/#!po=8.75000.

Kooxda, DFH. Aasaaska Bifidobacteria � Naqshadayaasha Caafimaadka, 5 Sebtembar 2019, blog.designsforhealth.com/node/1100.

Thursby, Elizabeth, iyo Nathalie Juge. �Hordhac ku saabsan Microbiota Gut Human.� Wargeyska Biochemical, Portland Press Ltd., 16 Meey 2017, www.ncbi.nlm.nih.gov/pmc/articles/PMC5433529/.

Wei, Yanxia, ​​iyo al. �Saamaynta Ka-hortagga ah ee Dufanka Bifidobacteria ee Ka-hortagga Sunta Clostridium difficile.� Xannibaadyada ku jira Microbiology, Frontiers Media SA, 8 Meey 2018, www.ncbi.nlm.nih.gov/pmc/articles/PMC5952185/.

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Ladnaanta Is-dhexgalka Casriga ah- Esse Quam Videri

Jaamacaddu waxay bixisaa xirfado caafimaad oo kala duwan oo kala duwan oo loogu talagalay daawaynta shaqaynaysa iyo isku-dhafka. Hadafkayagu waa inay ku wargeliyaan shakhsiyaadka raba inay isbeddel ku sameeyaan goobaha caafimaadka ee shaqaynaya xog aqoon leh oo ay bixin karaan.